242 papers
Infectious diseases represent one of the most dynamic frontiers in global health, covering everything from seasonal flu outbreaks to emerging viral threats that cross borders. This field focuses on how pathogens spread, how our immune systems respond, and the strategies scientists use to stop infections before they become epidemics. Because the science moves fast, waiting for traditional publication often means missing critical insights that could save lives.
At Gist.Science, we process every new preprint in this category directly from medRxiv to ensure you see the latest findings the moment they appear. Our team transforms these raw studies into both accessible plain-language explanations and detailed technical summaries, bridging the gap between complex research and public understanding. Below are the latest papers in infectious diseases, updated daily with fresh insights from the global research community.
This study of 45 Long COVID patients and matched controls found that while salivary hormone levels and viral shedding patterns did not differ significantly between groups, higher salivary HHV-6 DNA levels were positively associated with increased Long COVID symptom severity, anxiety, and depression.
This paper presents a multiscale ODE model of the 2026 Andes virus outbreak on the MV Hondius that identifies a critical immunopathological feedback loop as the driver of fatal cytokine storms, proposing a Wasserstein-based early-warning score and exogenous IL-10 supplementation as the most effective intervention to prevent vascular permeability failure.
This paper introduces a novel classification-based framework for evaluating wastewater-based surveillance as an event-detection system, demonstrating that a Bayesian exponential growth model substantially outperforms traditional methods in reliably identifying SARS-CoV-2 outbreak onsets and epidemic peaks across 281 U.S. counties.
This systematic review and meta-analysis synthesizes evidence on multi-organ post-acute sequelae across major respiratory and Aedes-borne diseases, revealing that infant RSV infection significantly increases asthma risk and dengue fever elevates risks for various neurological, psychiatric, autoimmune, and cardiovascular conditions, while highlighting substantial heterogeneity in study designs that limits broader comparability.
This retrospective study of over 320,000 adult drug-sensitive tuberculosis patients in Maharashtra, India, utilized programmatic data to identify that increasing age, male gender, lower body weight, comorbidities (HIV and diabetes), and substance use are significant predictors of both unfavorable treatment outcomes and mortality.
This study reveals that while pneumococcal conjugate vaccination triggers broad memory B cell expansion in peripheral blood, the germinal center response in lymph nodes is antigenically restricted to a limited number of specificities, suggesting that antigenic competition and extrafollicular responses play critical roles in adult immunity to multivalent vaccines.
By integrating clinical data and plasma proteomics from over 3,000 patients, this study establishes a digital twin framework that enables precise sepsis diagnosis, prognostic prediction, and personalized therapeutic recommendations at emergency department admission to advance precision medicine.
This paper reports the first documented detection of *Vibrio paracholerae* in a Costa Rican foodborne outbreak, highlighting the limitations of conventional diagnostic methods and emphasizing the critical need for genomic surveillance to accurately identify emerging enteropathogens.
This longitudinal study of 245 infants reveals that waning maternal antibodies differentially interfere with early influenza vaccination responses, while subsequent infections and vaccine timing significantly shape the development of durable, strain-specific immunity during the first two years of life.
In a study of adults with diabetes in South Africa, symptom-based screening for tuberculosis demonstrated poor sensitivity, while chest X-ray screening offered improved but still suboptimal sensitivity and reduced specificity in individuals with a history of TB.